• Abstracts Search Disclaimer

    The material presented at the CSRS Annual Meetings has been made available by the Cervical Spine Research Society for educational purposes only. The material is not intended to represent the only, nor necessarily best method or procedure appropriate for the medical situations discussed, but rather is intended to present an approach, view, statement or opinion of the faculty which may be helpful to others who face similar situations. The CSRS disclaims any and all liability for injury or other damages resulting to any individual attending the annual meeting and for all claims which may arise out of the use of the techniques demonstrated therein by such individuals whether these claims shall be asserted by physician or any other person.
  • Risk Factors and Functional Outcomes of Re-Intubation after Anterior Cervical Spine Surgery: Results from AOSpine North America Multicenter Study on 8,887 Patients

    Introduction: Anterior cervical spine surgery is one of the most common surgical procedures, and clinical recovery is generally satisfactory. However, the anterior approach does pose a risk for airway compromise requiring re-intubation due to postoperative soft-tissue edema or hematoma. Although this postoperative complication is suspected to be rare, it can result in poor and severe surgical outcomes when it does occur.
  • The Total Cost to the Healthcare System for the Treatment of Cervical Myelopathy

    Introduction: Cervical myelopathy is a common reasons patients over 65 years of age undergo cervical spine surgery, and in recent years there has been an increased awareness in the need to deliver not only high quality, but also cost effective treatment. Commonly this is reported as the cost per quality-adjusted life year gained, however, this method fails to account for the cost of complications associated with untreated cervical myelopathy.  Cervical myelopathy is a progressive disease, and if left untreated, over time it may lead to an increase in overall healthcare expenditures. The purpose of this study is to compare the total health care costs for patients treated with and without surgery for cervical myelopathy.
  • The Positive Effect of Continued Motion of a Cervical Artificial Disc Replacement on Radiographic Adjacent Level Degeneration at Seven-Year Follow-up

    Introduction: Development of symptomatic adjacent level degeneration (ALD) following anterior cervical discectomy and fusion (ACDF) remains a clinical concern. Cervical artificial disc replacement (C-ADR) maintains motion at the surgical level, and has been demonstrated to lower the incidence of developing radiographic ALD (R-ALD) than following ACDF. The purpose of this study is to compare the rates of progressive R-ALD 7 years post-surgery in patients treated with ProDisc-C, C-ADR or ACDF for one-level symptomatic cervical disc disease, and to examine the effect of final flexion-extension range of motion (ROM) of the C-ADR with the progression of R-ALD.
  • The Association Between Preoperative Mental Distress and Patient Reported Outcome in Patients Treated Surgically for Cervical Radiculopathy

    Introduction: Poor mental status has been proposed to affect postoperative outcome adversely. In this prospective study of a cohort from a multicenter RCT between cervical artificial disc replacement (ADR) and fusion (ACDF), the aim was to evaluate preoperative risk factors, with special reference to anxiety and depression. Methods: 151 patients were included in the RCT. 48% were women and mean age was 47 years. Primary outcome was measured with Neck Disability Index (NDI) and secondary outcome measures were EQ-5D, VAS arm and neck.
  • The Incidence and Associated Risk Factors of Cervical Spine Epidural Hematoma following Adult Trauma

    Introduction: Spinal epidural hematoma (SEH) is an uncommon clinical entity, but an important source of spinal cord compression, with several causes reported in the literature.  The objective of our study is to determine the incidence and associated risk factors for epidural hematoma in the setting of cervical spine trauma. Materials/Methods: We conducted a retrospective review of a prospectively collected state trauma registry; identifying all patients with cervical spine injuries who presented to a tertiary care Level I trauma center between the years 2010 and 2014.
  • Safety Assessment of NSCS Induced from Human PBMC-Derived IPS Cells for Transplantation Therapy for Spinal Cord Injury

    Purpose: Transplantation of human neural stem cells (NSCs) is now considered to be a promising treatment for various central nervous system disorders including spinal cord injury, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and brain infarction. In countries where fetal NSCs are not allowed to use due to ethical issues, iPS cells are a potential cell source of NSCs for cell therapy. Especially in Japan, an iPS cell bank is planned to be established from peripheral blood mononuclear cells (PBMCs) of immunologically preferable donors.
  • Is Obesity Correlated with Increased Complications following Cervical Surgery for Degenerative Conditions?

    Introduction: Obesity is a common comorbidity among spine patients. Previous studies have investigated correlations between obesity and complications in thoracolumbar spine surgery. To our knowledge no prospective studies have analyzed the direct effect of obesity on complications in patients undergoing elective cervical surgery. The impact of obesity on complications, operative time, and length of hospitalization remains uncertain in this population. The purpose of this study was to investigate the correlation between obesity, complications, length of stay, and operative time following elective anterior cervical discectomy and fusion (ACDF) for degenerative cervical conditions at a high-volume center.